CD27 anticorps
Aperçu rapide pour CD27 anticorps (ABIN7670002)
Antigène
Voir toutes CD27 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Purified Anti-Human CD27 Antibody[O323]
-
Isotype
- IgG1, kappa
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- ≥ 1 mg/mL
-
Buffer
- Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- avoid freeze / thaw cycles.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
-
Date de péremption
- 12 months
-
-
- CD27 (CD27 Molecule (CD27))
-
Autre désignation
- CD27
-
Sujet
- S152. LPFS,T-cell activation antigen CD,TNFRSF,S152.LPFS,CD27,S152,S152. LPFS2,T14,TNFRSF7,Tp55,S152.LPFS2,CD27L receptor,T-cell activation antigen CD27, S152, TNFRSF7,CD 27,CD27 antigen,CD27 Molecule,LPFS2,MGC20393,OTTHUMP00000238557,T cell activation antigen CD27,T cell antivation antigen S152,TNFRSF 7,TNFSF7,Tp 55,Tumor necrosis factor receptor superfamily member 7,The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
-
UniProt
- P26842
-
Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
Antigène
-